Human RAD18 protein (Recombinant) (N-GST & C-His) (STJP008809)

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STJP008809
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RAD18-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RAD18
Gene ID: 56852
Uniprot ID: RAD18_HUMAN
Immunogen Region: Gly12-Ser99
Immunogen: Homo sapiens (Human)
Protein Name E3 Ubiquitin-Protein Ligase Rad18
Postreplication Repair Protein Rad18
Hhr18
Hrad18
Ring Finger Protein 73
Ring-Type E3 Ubiquitin Transferase Rad18
Database Links Reactome: R-HSA-110314
Reactome: R-HSA-8866654
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Associates With Chromatin
Colocalizes With Slf1 In The Nucleus And To Centrosomes
Relocalizes With Slf1 To Nuclear Foci In Response To Dna Damage
Accumulates With The Slf1-Slf2 And Smc5-Smc6 Complexes At Replication-Coupled Dna Interstrand Repair And Dna Double-Strand Breaks (Dsbs) Sites On Chromatin In A Ubiquitin-Dependent Manner
Alternative Protein Names E3 Ubiquitin-Protein Ligase Rad18 protein
Postreplication Repair Protein Rad18 protein
Hhr18 protein
Hrad18 protein
Ring Finger Protein 73 protein
Ring-Type E3 Ubiquitin Transferase Rad18 protein
RAD18 protein
RNF73 protein

Information sourced from Uniprot.org

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