Human RAD18 protein (Recombinant) (N-GST & C-His) (STJP008809)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP008809
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General Information

Short DescriptionRecombinant-Human RAD18-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolRAD18
Gene ID56852
Uniprot IDRAD18_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGly12-Ser99

Additional Info

Protein Name E3 Ubiquitin-Protein Ligase Rad18
Postreplication Repair Protein Rad18
Hhr18
Hrad18
Ring Finger Protein 73
Ring-Type E3 Ubiquitin Transferase Rad18
Database Links Reactome: R-HSA-110314
Reactome: R-HSA-8866654
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Associates With Chromatin
Colocalizes With Slf1 In The Nucleus And To Centrosomes
Relocalizes With Slf1 To Nuclear Foci In Response To Dna Damage
Accumulates With The Slf1-Slf2 And Smc5-Smc6 Complexes At Replication-Coupled Dna Interstrand Repair And Dna Double-Strand Breaks (Dsbs) Sites On Chromatin In A Ubiquitin-Dependent Manner
Alternative Protein Names E3 Ubiquitin-Protein Ligase Rad18 protein
Postreplication Repair Protein Rad18 protein
Hhr18 protein
Hrad18 protein
Ring Finger Protein 73 protein
Ring-Type E3 Ubiquitin Transferase Rad18 protein
RAD18 protein
RNF73 protein

Information sourced from Uniprot.org

Citations

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