Name: Human PSME3 protein (Recombinant) (N-His) (STJP011681)
SKU: STJP011681
Availability: InStock

Human PSME3 protein (Recombinant) (N-His) (STJP011681)

SKU:

STJP011681

£208.50 - £1,163.50

Free Shipping

Short Description :	Recombinant-Human PSME3-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition.
Protein Name	Proteasome Activator Complex Subunit 3 11s Regulator Complex Subunit Gamma Reg-Gamma Activator Of Multicatalytic Protease Subunit 3 Ki Nuclear Autoantigen Proteasome Activator 28 Subunit Gamma Pa28g Pa28gamma
Database Links	Reactome: R-HSA-9907900
Cellular Localisation	Nucleus Cytoplasm Localizes To The Cytoplasm During Mitosis Following Nuclear Envelope Breakdown At This Distinct Stage Of The Cell Cycle Which Allows Its Interaction With Map3k3 Kinase
Alternative Protein Names	Proteasome Activator Complex Subunit 3 protein 11s Regulator Complex Subunit Gamma protein Reg-Gamma protein Activator Of Multicatalytic Protease Subunit 3 protein Ki Nuclear Autoantigen protein Proteasome Activator 28 Subunit Gamma protein Pa28g protein Pa28gamma protein PSME3 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP017426	Human PA28 gamma/PSME3 protein (Recombinant) (His-Tag) (STJP017426)	E.coli	SDS-PAGE
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP014345	Human HBZ protein (Recombinant) (N-His) (STJP014345)	E.coli	ELISA/WB
STJP014302	Human ALDH1A2 protein (Recombinant) (N-His) (STJP014302)	E.coli	ELISA/WB

Human PSME3 protein (Recombinant) (N-His) (STJP011681)

General Information