Human PIK3R5 protein (Recombinant) (N-His) (STJP008121)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PIK3R5-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PIK3R5 |
| Gene ID | 23533 |
| Uniprot ID | PI3R5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala666-Cys838 |
Additional Info
| Function | Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG. |
| Protein Name | Phosphoinositide 3-Kinase Regulatory Subunit 5Pi3-Kinase Regulatory Subunit 5Pi3-Kinase P101 SubunitPhosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory SubunitPtdins-3-Kinase Regulatory SubunitProtein Foap-2Ptdins-3-Kinase P101P101-Pi3k |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1257604Reactome: R-HSA-1660499Reactome: R-HSA-2219530Reactome: R-HSA-389357Reactome: R-HSA-392451Reactome: R-HSA-6811558Reactome: R-HSA-9027276Reactome: R-HSA-9927354 |
| Cellular Localisation | NucleusCytoplasmCell MembranePeripheral Membrane ProteinPredominantly Localized In The Nucleus In Absence Of Pik3cg/P120Colocalizes With Pik3cg/P120 In The CytoplasmTranslocated To The Plasma Membrane In A Beta-Gamma G Protein-Dependent Manner |
| Alternative Protein Names | Phosphoinositide 3-Kinase Regulatory Subunit 5 proteinPi3-Kinase Regulatory Subunit 5 proteinPi3-Kinase P101 Subunit proteinPhosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory Subunit proteinPtdins-3-Kinase Regulatory Subunit proteinProtein Foap-2 proteinPtdins-3-Kinase P101 proteinP101-Pi3k proteinPIK3R5 protein |
Information sourced from Uniprot.org