Human PIK3R5 protein (Recombinant) (N-His) (STJP008121)

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STJP008121
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Short Description :Recombinant-Human PIK3R5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:PIK3R5
Gene ID:23533
Uniprot ID:PI3R5_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala666-Cys838
Function Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG.
Protein Name Phosphoinositide 3-Kinase Regulatory Subunit 5
Pi3-Kinase Regulatory Subunit 5
Pi3-Kinase P101 Subunit
Phosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory Subunit
Ptdins-3-Kinase Regulatory Subunit
Protein Foap-2
Ptdins-3-Kinase P101
P101-Pi3k
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1257604
Reactome: R-HSA-1660499
Reactome: R-HSA-2219530
Reactome: R-HSA-389357
Reactome: R-HSA-392451
Reactome: R-HSA-6811558
Reactome: R-HSA-9027276
Reactome: R-HSA-9927354
Cellular Localisation Nucleus
Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Predominantly Localized In The Nucleus In Absence Of Pik3cg/P120
Colocalizes With Pik3cg/P120 In The Cytoplasm
Translocated To The Plasma Membrane In A Beta-Gamma G Protein-Dependent Manner
Alternative Protein Names Phosphoinositide 3-Kinase Regulatory Subunit 5 protein
Pi3-Kinase Regulatory Subunit 5 protein
Pi3-Kinase P101 Subunit protein
Phosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory Subunit protein
Ptdins-3-Kinase Regulatory Subunit protein
Protein Foap-2 protein
Ptdins-3-Kinase P101 protein
P101-Pi3k protein
PIK3R5 protein

Information sourced from Uniprot.org