Human PIK3R4 protein (Recombinant) (N-GST & C-His) (STJP009699)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PIK3R4-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PIK3R4 |
| Gene ID | 30849 |
| Uniprot ID | PI3R4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | His746-Asp812 |
Additional Info
| Post Translational Modifications | Myristoylated. Probably autophosphorylated. |
| Function | Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2. |
| Protein Name | Phosphoinositide 3-Kinase Regulatory Subunit 4Pi3-Kinase Regulatory Subunit 4Pi3-Kinase P150 SubunitPhosphoinositide 3-Kinase Adaptor Protein |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1632852Reactome: R-HSA-1660514Reactome: R-HSA-1660516Reactome: R-HSA-1660517Reactome: R-HSA-168138Reactome: R-HSA-5668599Reactome: R-HSA-9679504Reactome: R-HSA-9694676Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
| Cellular Localisation | Late EndosomeCytoplasmic VesicleAutophagosomeMembraneLipid-AnchorAs Component Of The Pi3k Complex I Localized To Pre-Autophagosome StructuresAs Component Of The Pi3k Complex Ii Localized Predominantly To EndosomesLocalizes Also To Discrete Punctae Along The Ciliary Axoneme |
| Alternative Protein Names | Phosphoinositide 3-Kinase Regulatory Subunit 4 proteinPi3-Kinase Regulatory Subunit 4 proteinPi3-Kinase P150 Subunit proteinPhosphoinositide 3-Kinase Adaptor Protein proteinPIK3R4 proteinVPS15 protein |
Information sourced from Uniprot.org