Human Perilipin-2 protein (Recombinant) (T7-Tag) (STJP018790)

SKU:
STJP018790
£134.50 - £738.50
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Short Description :Recombinant-Human Perilipin-2-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:PLIN2
Gene ID:123
Uniprot ID:PLIN2_HUMAN
Accession Number:NP_001113.2
Immunogen:Human
Immunogen Region:1-437aa
Immunogen Sequence:MASVAV DPQPSVVTRV VNLPLVSSTY DLMSSAYLST KDQYPYLKSV CEMAENGVKT ITSVAMTSAL PIIQKLEPQI AVANTYACKG LDRIEERLPI LNQPSTQIVA NAKGAVTGAK DAVTTTVTGA KDSVASTITG VMDKTKGAVT GSVEKTKSVV SGSINTVLGS RMMQLVSSGV ENALTKSELL VEQYLPLTEE ELEKEAKKVE GFDLVQ
Tissue Specificity Milk lipid globules.
Post Translational Modifications Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. Polyubiquitination of Nt-acetylatable A-PLIN2 by MARCHF6 lead to degradation by 26S proteasomes.
Function Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
Protein Name Perilipin-2
Adipophilin
Adipose Differentiation-Related Protein
Adrp
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-9613354
Reactome: R-HSA-9613829
Reactome: R-HSA-9615710
Reactome: R-HSA-9841922
Cellular Localisation Membrane
Peripheral Membrane Protein
Lipid Droplet
Alternative Protein Names Perilipin-2 protein
Adipophilin protein
Adipose Differentiation-Related Protein protein
Adrp protein
PLIN2 protein
ADFP protein

Information sourced from Uniprot.org