Human Perilipin-2 protein (Recombinant) (T7-Tag) (STJP018790)

Name: Human Perilipin-2 protein (Recombinant) (T7-Tag) (STJP018790)
SKU: STJP018790
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018790

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human Perilipin-2-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications.
Applications	SDS-PAGE/Denatured
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	PLIN2
Gene ID	123
Uniprot ID	PLIN2_HUMAN
Accession Number	NP_001113.2
Immunogen	Human
Immunogen Region	1-437aa
Immunogen Sequence	MASVAV DPQPSVVTRV VNLPLVSSTY DLMSSAYLST KDQYPYLKSV CEMAENGVKT ITSVAMTSAL PIIQKLEPQI AVANTYACKG LDRIEERLPI LNQPSTQIVA NAKGAVTGAK DAVTTTVTGA KDSVASTITG VMDKTKGAVT GSVEKTKSVV SGSINTVLGS RMMQLVSSGV ENALTKSELL VEQYLPLTEE ELEKEAKKVE GFDLVQ

Tissue Specificity	Milk lipid globules.
Post Translational Modifications	Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. Polyubiquitination of Nt-acetylatable A-PLIN2 by MARCHF6 lead to degradation by 26S proteasomes.
Function	Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.
Protein Name	Perilipin-2 Adipophilin Adipose Differentiation-Related Protein Adrp
Database Links	Reactome: R-HSA-1989781 Reactome: R-HSA-9613354 Reactome: R-HSA-9613829 Reactome: R-HSA-9615710 Reactome: R-HSA-9841922
Cellular Localisation	Membrane Peripheral Membrane Protein Lipid Droplet
Alternative Protein Names	Perilipin-2 protein Adipophilin protein Adipose Differentiation-Related Protein protein Adrp protein PLIN2 protein ADFP protein

Information sourced from Uniprot.org