Human PDE6D protein (Recombinant) (His-Tag) (STJP016693)

Name: Human PDE6D protein (Recombinant) (His-Tag) (STJP016693)
SKU: STJP016693
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016693

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Short Description	Recombinant-Human PDE6D-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 100mM NaCl
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	PDE6D
Gene ID	5147
Uniprot ID	PDE6D_HUMAN
Accession Number	NP_002592
Immunogen	Human
Immunogen Region	1-150aa
Immunogen Sequence	MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV

Tissue Specificity	Widely expressed. Detected in various tissues including spleen, prostate gland, testis, ovary, small intestine, colon, retina, and peripheral blood.
Function	Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Required for RAB28 localization to the cone cell outer segments in the retina. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
Protein Name	Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta Gmp-Pde Delta Protein P17
Database Links	Reactome: R-HSA-5624958 Reactome: R-HSA-9648002
Cellular Localisation	Cytoplasm Cytosol Cytoplasmic Vesicle Membrane Peripheral Membrane Protein Cytoskeleton Cilium Basal Body
Alternative Protein Names	Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta protein Gmp-Pde Delta protein Protein P17 protein PDE6D protein PDED protein

Information sourced from Uniprot.org