Human PCSK5 protein (Recombinant) (N-His) (STJP005792)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PCSK5-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PCSK5 |
| Gene ID | 5125 |
| Uniprot ID | PCSK5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp115-Met454 |
Additional Info
| Function | Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXXKRR consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. |
| Protein Name | Proprotein Convertase Subtilisin/Kexin Type 5Proprotein Convertase 5Pc5Proprotein Convertase 6Pc6Hpc6Subtilisin/Kexin-Like Protease Pc5 |
| Database Links | Reactome: R-HSA-167060Reactome: R-HSA-8963889 |
| Cellular Localisation | Isoform Pc6a: SecretedSecreted Through The Regulated Secretory PathwayIsoform Pc6b: Endomembrane SystemSingle-Pass Type I Membrane ProteinType I Membrane Protein Localized To A Paranuclear Post-Golgi Network Compartment In Communication With Early Endosomes |
| Alternative Protein Names | Proprotein Convertase Subtilisin/Kexin Type 5 proteinProprotein Convertase 5 proteinPc5 proteinProprotein Convertase 6 proteinPc6 proteinHpc6 proteinSubtilisin/Kexin-Like Protease Pc5 proteinPCSK5 proteinPC5 proteinPC6 protein |
Information sourced from Uniprot.org