Human NFKBIE protein (Recombinant) (N-His) (STJP003135)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NFKBIE-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NFKBIE |
| Gene ID | 4794 |
| Uniprot ID | IKBE_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg207-Pro440 |
Additional Info
| Post Translational Modifications | Serine phosphorylated.followed by proteasome-dependent degradation. |
| Function | Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity. Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50-c-Rel) complexes. Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development. |
| Protein Name | Nf-Kappa-B Inhibitor EpsilonNf-Kappa-BieI-Kappa-B-EpsilonIkb-EIkb-EpsilonIkappabepsilon |
| Database Links | Reactome: R-HSA-1169091 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Nf-Kappa-B Inhibitor Epsilon proteinNf-Kappa-Bie proteinI-Kappa-B-Epsilon proteinIkb-E proteinIkb-Epsilon proteinIkappabepsilon proteinNFKBIE proteinIKBE protein |
Information sourced from Uniprot.org