Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human NFKBIE-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | NFKBIE |
Gene ID: | 4794 |
Uniprot ID: | IKBE_HUMAN |
Immunogen Region: | Arg207-Pro440 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | Serine phosphorylated.followed by proteasome-dependent degradation. |
Function | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. |
Protein Name | Nf-Kappa-B Inhibitor EpsilonNf-Kappa-BieI-Kappa-B-EpsilonIkb-EIkb-EpsilonIkappabepsilon |
Database Links | Reactome: R-HSA-1169091 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Nf-Kappa-B Inhibitor Epsilon proteinNf-Kappa-Bie proteinI-Kappa-B-Epsilon proteinIkb-E proteinIkb-Epsilon proteinIkappabepsilon proteinNFKBIE proteinIKBE protein |
Information sourced from Uniprot.org