Human NDOR1 protein (Recombinant) (N-His) (STJP008147)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NDOR1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NDOR1 |
| Gene ID | 27158 |
| Uniprot ID | NDOR1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu154 |
Additional Info
| Function | NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the 2Fe-2S cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the 2Fe-2S cluster of CISD1 and activate this protein implicated in Fe/S cluster repair. In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A. |
| Protein Name | Nadph-Dependent Diflavin Oxidoreductase 1Nadph-Dependent Fmn And Fad-Containing OxidoreductaseNovel Reductase 1 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | CytoplasmPerinuclear RegionConcentrated In Perinuclear Structure |
| Alternative Protein Names | Nadph-Dependent Diflavin Oxidoreductase 1 proteinNadph-Dependent Fmn And Fad-Containing Oxidoreductase proteinNovel Reductase 1 proteinNDOR1 proteinNR1 protein |
Information sourced from Uniprot.org