Human NDOR1 protein (Recombinant) (N-His) (STJP008147)

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STJP008147
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NDOR1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NDOR1
Gene ID: 27158
Uniprot ID: NDOR1_HUMAN
Immunogen Region: Met1-Leu154
Immunogen: Homo sapiens (Human)
Function NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the 2Fe-2S cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the 2Fe-2S cluster of CISD1 and activate this protein implicated in Fe/S cluster repair. In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A.
Protein Name Nadph-Dependent Diflavin Oxidoreductase 1
Nadph-Dependent Fmn And Fad-Containing Oxidoreductase
Novel Reductase 1
Database Links Reactome: R-HSA-2564830
Cellular Localisation Cytoplasm
Perinuclear Region
Concentrated In Perinuclear Structure
Alternative Protein Names Nadph-Dependent Diflavin Oxidoreductase 1 protein
Nadph-Dependent Fmn And Fad-Containing Oxidoreductase protein
Novel Reductase 1 protein
NDOR1 protein
NR1 protein

Information sourced from Uniprot.org

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