Human MOGAT2 (Monoacylglycerol-O-acyltransferase 2) Sandwich ELISA Kit (STJE0010705)
SPECIFICATIONS
General Information
| Short Description | This MOGAT2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.059ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | MOGAT2 |
| Gene ID | 80168 |
| Uniprot ID | MOGT2_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Highly expressed in liver, small intestine, colon, stomach and kidney. |
| Post Translational Modifications | |
| Function | Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0 at sn-2. Able to use 1-monoalkylglycerol (1-MAkG, 1-O-alkylglycerol) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG, 1-O-alkyl-3-acylglycerol or 1-O-alkyl-2-acylglycerol) and subsequently, with lower efficiency, may add another acyl chain producing monoalkyl-diacylglycerol (MADAG, 1-O-alkyl-2,3-diacylglycerol). Possesses weak but significant activity with diacylglycerol as substrate, producing triacylglycerol (triacyl-sn-glycerol). |
| Protein Name | 2-Acylglycerol O-Acyltransferase 2Acyl-Coa -Monoacylglycerol Acyltransferase 2Mgat2Hmgat2Diacylglycerol O-Acyltransferase Candidate 5Hdc5Diacylglycerol Acyltransferase 2-Like Protein 5Monoacylglycerol O-Acyltransferase 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear Region |
| Alternative ELISA Names | 2-Acylglycerol O-Acyltransferase 2 ELISA kitAcyl-Coa -Monoacylglycerol Acyltransferase 2 ELISA kitMgat2 ELISA kitHmgat2 ELISA kitDiacylglycerol O-Acyltransferase Candidate 5 ELISA kitHdc5 ELISA kitDiacylglycerol Acyltransferase 2-Like Protein 5 ELISA kitMonoacylglycerol O-Acyltransferase 2 ELISA kitMOGAT2 ELISA kitDC5 ELISA kitDGAT2L5 ELISA kit |
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Information sourced from Uniprot.org