| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.059ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This MOGAT2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
MOGAT2 |
| Gene ID: |
80168 |
| Uniprot ID: |
MOGT2_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly expressed in liver, small intestine, colon, stomach and kidney. |
| Post Translational Modifications | |
| Function | Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0 at sn-2. Able to use 1-monoalkylglycerol (1-MAkG, 1-O-alkylglycerol) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG, 1-O-alkyl-3-acylglycerol or 1-O-alkyl-2-acylglycerol) and subsequently, with lower efficiency, may add another acyl chain producing monoalkyl-diacylglycerol (MADAG, 1-O-alkyl-2,3-diacylglycerol). Possesses weak but significant activity with diacylglycerol as substrate, producing triacylglycerol (triacyl-sn-glycerol). |
| Protein Name | 2-Acylglycerol O-Acyltransferase 2Acyl-Coa -Monoacylglycerol Acyltransferase 2Mgat2Hmgat2Diacylglycerol O-Acyltransferase Candidate 5Hdc5Diacylglycerol Acyltransferase 2-Like Protein 5Monoacylglycerol O-Acyltransferase 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear Region |
| Alternative ELISA Names | 2-Acylglycerol O-Acyltransferase 2 ELISA kitAcyl-Coa -Monoacylglycerol Acyltransferase 2 ELISA kitMgat2 ELISA kitHmgat2 ELISA kitDiacylglycerol O-Acyltransferase Candidate 5 ELISA kitHdc5 ELISA kitDiacylglycerol Acyltransferase 2-Like Protein 5 ELISA kitMonoacylglycerol O-Acyltransferase 2 ELISA kitMOGAT2 ELISA kitDC5 ELISA kitDGAT2L5 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
