| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in 10mM HEPES, 5mM CaCl2, 150mM NaCl (pH 7.5). Normally 8% Trehalose is added as protectant before lyophilisation. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method |
| Immunoreactivity: | Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (RD, Catalog # ES001). The specific activity is >812 pmol/min/µg, as measured under the described conditions. |
| Gene Symbol: | MMP7 |
| Gene ID: | 4316 |
| Uniprot ID: | MMP7_HUMAN |
| Immunogen Region: | Met1-Lys267 |
| Immunogen: | Recombinant Recombinant Human MMP-7 Protein is produced by CHO Cells expression system. The target protein is expressed with sequence (Met1-Lys267) of Human MMP-7 (Accession #NP_002414.1) fused with a His tag at the C-terminus. |
| Immunogen Sequence: | EAEEDGDLQCLCVKTTSQVR PRHITSLEVIKAGPHCPTAQ LIATLKNGRKICLDLQAPLY KKIIKKLLES |
| Function | Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. |
| Protein Name | MatrilysinMatrinMatrix Metalloproteinase-7Mmp-7Pump-1 ProteaseUterine Metalloproteinase |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-2022090Reactome: R-HSA-9009391 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Matrilysin proteinMatrin proteinMatrix Metalloproteinase-7 proteinMmp-7 proteinPump-1 Protease proteinUterine Metalloproteinase proteinMMP7 proteinMPSL1 proteinPUMP1 protein |
Information sourced from Uniprot.org
