Human MMP-7 protein (Recombinant) (C-His) (STJP003007)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Recombinant Human MMP-7 Protein is produced by CHO Cells expression system. The target protein is expressed with sequence (Met1-Lys267) of Human MMP-7 (Accession #NP_002414.1) fused with a His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human MMP-7-C-His protein was developed in hek293 cells using the region Met1-Lys267. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in 10mM HEPES, 5mM CaCl2, 150mM NaCl (pH 7.5). Normally 8% Trehalose is added as protectant before lyophilisation. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (RD, Catalog # ES001). The specific activity is >812 pmol/min/µg, as measured under the described conditions. |
| Determination Method | < 0.01 EU/Mu g of the protein by LAL method |
Target Information
| Gene Symbol | MMP7 |
| Gene ID | 4316 |
| Uniprot ID | MMP7_HUMAN |
| Immunogen | Recombinant Recombinant Human MMP-7 Protein is produced by CHO Cells expression system. The target protein is expressed with sequence (Met1-Lys267) of Human MMP-7 (Accession #NP_002414.1) fused with a His tag at the C-terminus. |
| Immunogen Region | Met1-Lys267 |
| Immunogen Sequence | EAEEDGDLQCLCVKTTSQVR PRHITSLEVIKAGPHCPTAQ LIATLKNGRKICLDLQAPLY KKIIKKLLES |
Additional Info
| Function | Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. |
| Protein Name | MatrilysinMatrinMatrix Metalloproteinase-7Mmp-7Pump-1 ProteaseUterine Metalloproteinase |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-2022090Reactome: R-HSA-9009391 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Matrilysin proteinMatrin proteinMatrix Metalloproteinase-7 proteinMmp-7 proteinPump-1 Protease proteinUterine Metalloproteinase proteinMMP7 proteinMPSL1 proteinPUMP1 protein |
Information sourced from Uniprot.org