Human MED21 protein (Recombinant) (His-Tag) (STJP018225)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MED21-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MED21 |
| Gene ID | 9412 |
| Uniprot ID | MED21_HUMAN |
| Accession Number | NP_004255 |
| Immunogen | Human |
| Immunogen Region | 1-144aa |
| Immunogen Sequence |
Additional Info
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 21Mediator Complex Subunit 21Rna Polymerase Ii Holoenzyme Component Srb7Rnapii Complex Component Srb7Hsrb7 |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Mediator Of Rna Polymerase Ii Transcription Subunit 21 proteinMediator Complex Subunit 21 proteinRna Polymerase Ii Holoenzyme Component Srb7 proteinRnapii Complex Component Srb7 proteinHsrb7 proteinMED21 proteinSRB7 proteinSURB7 protein |
Information sourced from Uniprot.org