Name: Human MBD3 protein (Recombinant) (His-Tag) (STJP017855)
SKU: STJP017855
Availability: InStock

Human MBD3 protein (Recombinant) (His-Tag) (STJP017855)

SKU:

STJP017855

£158.50 - £965.50

Free Shipping

Short Description :	Recombinant-Human MBD3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	0.25 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% Glycerol, 1mM DTT, 1mM EDTA
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	MBD3
Gene ID:	53615
Uniprot ID:	MBD3_HUMAN
Accession Number:	NP_003917
Immunogen:	Human
Immunogen Region:	1-291aa
Immunogen Sequence:	MGSSHHHHHH SSGLVPRGSH MGSMERKRWE CPALPQGWER EEVPRRSGLS AGHRDVFYYS PSGKKFRSKP QLARYLGGSM DLSTFDFRTG KMLMSKMNKS RQRVRYDSSN QVKGKPDLNT ALPVRQTASI FKQPVTKITN HPSNKVKSDP QKAVDQPRQL FWEKKLSGLN AFDIAEELVK TMDLPKGLQG VGPGCTDETL LSAIASALHT STMPITGQLS AAVEKNPG

Function	Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to methylated DNA by itself. Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
Protein Name	Methyl-Cpg-Binding Domain Protein 3 Methyl-Cpg-Binding Protein Mbd3
Database Links	Reactome: R-HSA-3214815 Reactome: R-HSA-427389 Reactome: R-HSA-6804758 Reactome: R-HSA-73762 Reactome: R-HSA-8943724 Reactome: R-HSA-9679191 Reactome: R-HSA-9843940 Reactome: R-HSA-9844594 Reactome: R-HSA-9845323
Cellular Localisation	Nucleus Chromosome Nuclear In Discrete Foci Detected On Chromatin At Promoter Regions Of Active Genes
Alternative Protein Names	Methyl-Cpg-Binding Domain Protein 3 protein Methyl-Cpg-Binding Protein Mbd3 protein MBD3 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP008923	Human MBD3 protein (Recombinant) (N-His) (STJP008923)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP019170	Human FGB protein (Recombinant) (His-Tag) (STJP019170)	E.coli	SDS-PAGE
STJP019149	Human PYCR2 protein (Recombinant) (His-Tag) (STJP019149)	E.coli	SDS-PAGE
STJP019163	Human ALDH6A1 protein (Recombinant) (His-Tag) (STJP019163)	E.coli	SDS-PAGE
STJP019189	Human UBE2Q2 protein (Recombinant) (His-Tag) (STJP019189)	E.coli	SDS-PAGE

Human MBD3 protein (Recombinant) (His-Tag) (STJP017855)

General Information