Human MARCO protein (Recombinant) (N-His) (STJP020329)

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STJP020329-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: MARCO
Gene ID: 8685
Uniprot ID: MARCO_HUMAN
Immunogen Region: Ser405-Val520
Immunogen: Recombinant Human MARCO Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Ser405-Val520.
Tissue Specificity Expressed in alveolar macrophages (at protein level). Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen.
Post Translational Modifications N-glycosylated.
Function Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2.
Protein Name Macrophage Receptor Marco
Macrophage Receptor With Collagenous Structure
Scavenger Receptor Class A Member 2
Database Links Reactome: R-HSA-3000480
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Macrophage Receptor Marco protein
Macrophage Receptor With Collagenous Structure protein
Scavenger Receptor Class A Member 2 protein
MARCO protein
SCARA2 protein

Information sourced from Uniprot.org

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