Human MARCO protein (Recombinant) (N-His) (STJP020329)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human MARCO Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Ser405-Val520.
General Information
| Short Description | Recombinant-Human MARCO-N-His protein was developed in hek293 cells using the region Ser405-Val520. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | MARCO |
| Gene ID | 8685 |
| Uniprot ID | MARCO_HUMAN |
| Immunogen | Recombinant Human MARCO Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Ser405-Val520. |
| Immunogen Region | Ser405-Val520 |
Additional Info
| Tissue Specificity | Expressed in alveolar macrophages (at protein level). Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen. |
| Post Translational Modifications | N-glycosylated. |
| Function | Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. |
| Protein Name | Macrophage Receptor MarcoMacrophage Receptor With Collagenous StructureScavenger Receptor Class A Member 2 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Macrophage Receptor Marco proteinMacrophage Receptor With Collagenous Structure proteinScavenger Receptor Class A Member 2 proteinMARCO proteinSCARA2 protein |
Information sourced from Uniprot.org