Human MAGEA1 protein (Recombinant) (N-His) (STJP004744)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MAGEA1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MAGEA1 |
| Gene ID | 4100 |
| Uniprot ID | MAGA1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ile102-Val309 |
Additional Info
| Function | May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. |
| Protein Name | Melanoma-Associated Antigen 1Antigen Mz2-ECancer/Testis Antigen 1.1Ct1.1Mage-1 Antigen |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Melanoma-Associated Antigen 1 proteinAntigen Mz2-E proteinCancer/Testis Antigen 1.1 proteinCt1.1 proteinMage-1 Antigen proteinMAGEA1 proteinMAGE1 proteinMAGE1A protein |
Information sourced from Uniprot.org