Human MAGEA1 protein (Recombinant) (N-His) (STJP004744)

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STJP004744
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MAGEA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MAGEA1
Gene ID: 4100
Uniprot ID: MAGA1_HUMAN
Immunogen Region: Ile102-Val309
Immunogen: Homo sapiens (Human)
Function May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Protein Name Melanoma-Associated Antigen 1
Antigen Mz2-E
Cancer/Testis Antigen 1.1
Ct1.1
Mage-1 Antigen
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names Melanoma-Associated Antigen 1 protein
Antigen Mz2-E protein
Cancer/Testis Antigen 1.1 protein
Ct1.1 protein
Mage-1 Antigen protein
MAGEA1 protein
MAGE1 protein
MAGE1A protein

Information sourced from Uniprot.org