SDS-PAGE gel of recombinant human LYPLA2 protein under reducing conditions stained with Coomassie blue

Human LYPLA2 protein (Recombinant) (His-Tag) (STJP017063)

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STJP017063
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Short Description :Recombinant-Human LYPLA2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 100mM NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:LYPLA2
Gene ID:11313
Uniprot ID:LYPA2_HUMAN
Accession Number:NP_009191.1
Immunogen:Human
Immunogen Region:1-231aa
Immunogen Sequence: MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYP
Tissue Specificity Expressed in various breast cancer cell lines.
Function Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Protein Name Acyl-Protein Thioesterase 2
Apt-2
Lysophospholipase Ii
Lpl-Ii
Lysopla Ii
Palmitoyl-Protein Hydrolase
Database Links Reactome: R-HSA-373760
Cellular Localisation Cytoplasm
Alternative Protein Names Acyl-Protein Thioesterase 2 protein
Apt-2 protein
Lysophospholipase Ii protein
Lpl-Ii protein
Lysopla Ii protein
Palmitoyl-Protein Hydrolase protein
LYPLA2 protein
APT2 protein

Information sourced from Uniprot.org

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