Human LYPLA2 protein (Recombinant) (His-Tag) (STJP017063)

Name: Human LYPLA2 protein (Recombinant) (His-Tag) (STJP017063)
SKU: STJP017063
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017063

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Short Description	Recombinant-Human LYPLA2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 100mM NaCl
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	LYPLA2
Gene ID	11313
Uniprot ID	LYPA2_HUMAN
Accession Number	NP_009191.1
Immunogen	Human
Immunogen Region	1-231aa
Immunogen Sequence	MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYP

Tissue Specificity	Expressed in various breast cancer cell lines.
Function	Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Protein Name	Acyl-Protein Thioesterase 2 Apt-2 Lysophospholipase Ii Lpl-Ii Lysopla Ii Palmitoyl-Protein Hydrolase
Database Links	Reactome: R-HSA-373760
Cellular Localisation	Cytoplasm
Alternative Protein Names	Acyl-Protein Thioesterase 2 protein Apt-2 protein Lysophospholipase Ii protein Lpl-Ii protein Lysopla Ii protein Palmitoyl-Protein Hydrolase protein LYPLA2 protein APT2 protein

Information sourced from Uniprot.org