| Short Description : | Recombinant-Human LSS-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | LSS |
| Gene ID: | 4047 |
| Uniprot ID: | LSS_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Asp388-Pro549 |
| Function | Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. |
| Protein Name | Lanosterol Synthase2 -3-Epoxysqualene--Lanosterol CyclaseOxidosqualene--Lanosterol CyclaseOscHosc |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane Protein |
| Alternative Protein Names | Lanosterol Synthase protein2 -3-Epoxysqualene--Lanosterol Cyclase proteinOxidosqualene--Lanosterol Cyclase proteinOsc proteinHosc proteinLSS proteinOSC protein |
Information sourced from Uniprot.org