Function | Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. |
Protein Name | Lanosterol Synthase2 -3-Epoxysqualene--Lanosterol CyclaseOxidosqualene--Lanosterol CyclaseOscHosc |
Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane Protein |
Alternative Protein Names | Lanosterol Synthase protein2 -3-Epoxysqualene--Lanosterol Cyclase proteinOxidosqualene--Lanosterol Cyclase proteinOsc proteinHosc proteinLSS proteinOSC protein |
Information sourced from Uniprot.org