Human LSS protein (Recombinant) (N-His) (STJP004789)

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STJP004789
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LSS-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LSS
Gene ID: 4047
Uniprot ID: LSS_HUMAN
Immunogen Region: Asp388-Pro549
Immunogen: Homo sapiens (Human)
Function Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
Protein Name Lanosterol Synthase
2 -3-Epoxysqualene--Lanosterol Cyclase
Oxidosqualene--Lanosterol Cyclase
Osc
Hosc
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-2426168
Cellular Localisation Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Alternative Protein Names Lanosterol Synthase protein
2 -3-Epoxysqualene--Lanosterol Cyclase protein
Oxidosqualene--Lanosterol Cyclase protein
Osc protein
Hosc protein
LSS protein
OSC protein

Information sourced from Uniprot.org