SDS-PAGE gel of recombinant human LILRA3 CD85e protein 3ug reducing conditions Coomassie blue stain

Human LILRA3/CD85e protein (Recombinant) (hIgG-His-Tag) (STJP019567)

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STJP019567
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Short Description :Recombinant-Human LILRA3/CD85e-hIgG-His-Tag protein was developed from hek293 cells and has a target region of hIgG-His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:HEK293 Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:< 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol:LILRA3
Gene ID:11026
Uniprot ID:LIRA3_HUMAN
Accession Number:NP_006856.3
Immunogen:Human
Immunogen Region:24-439aa
Immunogen Sequence:GPLPKPT LWAEPGSVIT QGSPVTLRCQ GSLETQEYHL YREKKTALWI TRIPQELVKK GQFPILSITW EHAGRYCCIY GSHTAGLSES SDPLELVVTG AYSKPTLSAL PSPVVTSGGN VTIQCDSQVA FDGFILCKEG EDEHPQCLNS HSHARGSSRA IFSVGPVSPS RRWSYRCYGY DSRAPYVWSL PSDLLGLLVP GVSKKPSLSV QPGPVVAPGE KLTFQC
Tissue Specificity Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.
Post Translational Modifications N-glycosylation is required for ligand binding.
Function Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3
Cd85 Antigen-Like Family Member E
Immunoglobulin-Like Transcript 6
Ilt-6
Leukocyte Immunoglobulin-Like Receptor 4
Lir-4
Monocyte Inhibitory Receptor Hm43/Hm31
Cd Antigen Cd85e
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 protein
Cd85 Antigen-Like Family Member E protein
Immunoglobulin-Like Transcript 6 protein
Ilt-6 protein
Leukocyte Immunoglobulin-Like Receptor 4 protein
Lir-4 protein
Monocyte Inhibitory Receptor Hm43/Hm31 protein
Cd Antigen Cd85e protein
LILRA3 protein
ILT6 protein
LIR4 protein

Information sourced from Uniprot.org

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