| Short Description : | Recombinant-Human LIF-His-GST-Tag protein was developed from e.coli and has a target region of His-GST-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol, 50mM NaCl |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIF |
| Gene ID: | 3976 |
| Uniprot ID: | LIF_HUMAN |
| Accession Number: | NP_002300 |
| Immunogen: | Human |
| Immunogen Region: | 23-202aa |
| Immunogen Sequence: | MHHHHHHMSP ILGYWKIKGL VQPTRLLLEY LEEKYEEHLY ERDEGDKWRN KKFELGLEFP NLPYYIDGDV KLTQSMAIIR YIADKHNMLG GCPKERAEIS MLEGAVLDIR YGVSRIAYSK DFETLKVDFL SKLPEMLKMF EDRLCHKTYL NGDHVTHPDF MLYDALDVVL YMDPMCLDAF PKLVCFKKRI EAIPQIDKYL KSSKYIAWPL QGWQATFGGG DHPPKSDL |
| Function | LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. |
| Protein Name | Leukemia Inhibitory FactorLifDifferentiation-Stimulating FactorD FactorMelanoma-Derived Lpl InhibitorMlpliEmfilermin |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-6785807Reactome: R-HSA-6788467 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Leukemia Inhibitory Factor proteinLif proteinDifferentiation-Stimulating Factor proteinD Factor proteinMelanoma-Derived Lpl Inhibitor proteinMlpli proteinEmfilermin proteinLIF proteinHILDA protein |
Information sourced from Uniprot.org
