Human LIF protein (Recombinant) (His-GST-Tag) (STJP016896)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP016896
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General Information

Short DescriptionRecombinant-Human LIF-His-GST-Tag protein was developed from e.coli and has a target region of His-GST-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol, 50mM NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolLIF
Gene ID3976
Uniprot IDLIF_HUMAN
Accession NumberNP_002300
ImmunogenHuman
Immunogen Region23-202aa
Immunogen SequenceMHHHHHHMSP ILGYWKIKGL VQPTRLLLEY LEEKYEEHLY ERDEGDKWRN KKFELGLEFP NLPYYIDGDV KLTQSMAIIR YIADKHNMLG GCPKERAEIS MLEGAVLDIR YGVSRIAYSK DFETLKVDFL SKLPEMLKMF EDRLCHKTYL NGDHVTHPDF MLYDALDVVL YMDPMCLDAF PKLVCFKKRI EAIPQIDKYL KSSKYIAWPL QGWQATFGGG DHPPKSDL

Additional Info

Function LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Protein Name Leukemia Inhibitory Factor
Lif
Differentiation-Stimulating Factor
D Factor
Melanoma-Derived Lpl Inhibitor
Mlpli
Emfilermin
Database Links Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-6788467
Cellular Localisation Secreted
Alternative Protein Names Leukemia Inhibitory Factor protein
Lif protein
Differentiation-Stimulating Factor protein
D Factor protein
Melanoma-Derived Lpl Inhibitor protein
Mlpli protein
Emfilermin protein
LIF protein
HILDA protein

Information sourced from Uniprot.org

Citations

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