Human LCT protein (Recombinant) (N-His) (STJP010843)

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STJP010843
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LCT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LCT
Gene ID: 3938
Uniprot ID: LPH_HUMAN
Immunogen Region: Ser20-Gly336
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Broad specificity glycosidase of the intestinal brush border membrane that hydrolyzes lactose, the main sugar in mammalian milk, to produce D-glucose and D-galactose. The mature protein is composed of two domains that catalyze the hydrolysis of beta-glucopyranosides and beta-galactopyranosides, with a preference for hydrophilic aglycones (in lactose and cellobiose) for one domain and hydrophobic aglycones (in phlorizin and glycosylceramides) for the other.
Protein Name Lactase/Phlorizin Hydrolase
Lactase/Glycosylceramidase Includes - Lactase - Glycosylceramidase
Phlorizin Hydrolase
Database Links Reactome: R-HSA-189085
Reactome: R-HSA-5659898
Cellular Localisation Apical Cell Membrane
Single-Pass Type I Membrane Protein
Brush Border
Alternative Protein Names Lactase/Phlorizin Hydrolase protein
Lactase/Glycosylceramidase Includes - Lactase - Glycosylceramidase protein
Phlorizin Hydrolase protein
LCT protein
LPH protein

Information sourced from Uniprot.org

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