Human LCT protein (Recombinant) (N-His) (STJP010843)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LCT-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LCT |
| Gene ID | 3938 |
| Uniprot ID | LPH_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser20-Gly336 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Broad specificity glycosidase of the intestinal brush border membrane that hydrolyzes lactose, the main sugar in mammalian milk, to produce D-glucose and D-galactose. The mature protein is composed of two domains that catalyze the hydrolysis of beta-glucopyranosides and beta-galactopyranosides, with a preference for hydrophilic aglycones (in lactose and cellobiose) for one domain and hydrophobic aglycones (in phlorizin and glycosylceramides) for the other. |
| Protein Name | Lactase/Phlorizin HydrolaseLactase/Glycosylceramidase Includes - Lactase - GlycosylceramidasePhlorizin Hydrolase |
| Database Links | Reactome: R-HSA-189085Reactome: R-HSA-5659898 |
| Cellular Localisation | Apical Cell MembraneSingle-Pass Type I Membrane ProteinBrush Border |
| Alternative Protein Names | Lactase/Phlorizin Hydrolase proteinLactase/Glycosylceramidase Includes - Lactase - Glycosylceramidase proteinPhlorizin Hydrolase proteinLCT proteinLPH protein |
Information sourced from Uniprot.org