Human L1CAM (L1CAM) Antibody Pair (STJAP00888)
General Information
| Short Description | This L1CAM antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R08-9S-2/R05-7G-7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | L1CAM |
| Gene ID | 3897 |
| Uniprot ID | L1CAM_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Function | Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. |
| Protein Name | Neural Cell Adhesion Molecule L1N-Cam-L1Ncam-L1Cd Antigen Cd171 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-373760Reactome: R-HSA-437239Reactome: R-HSA-445095Reactome: R-HSA-445144 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionGrowth ConeAxonDendriteColocalized With Shtn1 In Close Apposition With Actin Filaments In Filopodia And Lamellipodia Of Axonalne Growth Cones Of Hippocampal NeuronsIn NeuronsDetected Predominantly In Axons And Cell BodyWeak Localization To Dendrites |
| Alternative Antibody Pair Names | Neural Cell Adhesion Molecule L1 antibody pairN-Cam-L1 antibody pairNcam-L1 antibody pairCd Antigen Cd171 antibody pairL1CAM antibody pairCAML1 antibody pairMIC5 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human L1CAM (L1CAM) Antibody Pair (STJAP00888)
This antibody pair detects human L1CAM (UniProt P32004) and has confirmed reactivity for human samples only. No cross-reactivity data for other species is provided.
Both antibodies are rabbit monoclonal IgGs (clone IDs R08-9S-2 and R05-7G-7), supplied unconjugated and formulated in 0.01M PBS at pH 7.2. Both are affinity purified; concentration is not specified in the product details and should be confirmed with the supplier upon ordering.
This antibody pair is validated for use in ELISA. No additional assay formats are listed in the product details.
Working dilutions for both antibodies are determined by the end user and are not predefined in the product specifications. Titration experiments are recommended to establish optimal concentrations for your specific assay conditions.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.