| Host: | Rabbit/Rabbit |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | This L1CAM antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Clonality : | Monoclonal/Monoclonal |
| Clone ID : | R08-9S-2/R05-7G-7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.2 |
| Purification: | Affinity Purification |
| Dilution Range: | Determined by end user |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | L1CAM |
| Gene ID: | 3897 |
| Uniprot ID: | L1CAM_HUMAN |
| Immunogen: | Recombinant protein |
| Function | Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. |
| Protein Name | Neural Cell Adhesion Molecule L1N-Cam-L1Ncam-L1Cd Antigen Cd171 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-373760Reactome: R-HSA-437239Reactome: R-HSA-445095Reactome: R-HSA-445144 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionGrowth ConeAxonDendriteColocalized With Shtn1 In Close Apposition With Actin Filaments In Filopodia And Lamellipodia Of Axonalne Growth Cones Of Hippocampal NeuronsIn NeuronsDetected Predominantly In Axons And Cell BodyWeak Localization To Dendrites |
| Alternative Antibody Pair Names | Neural Cell Adhesion Molecule L1 antibody pairN-Cam-L1 antibody pairNcam-L1 antibody pairCd Antigen Cd171 antibody pairL1CAM antibody pairCAML1 antibody pairMIC5 antibody pair |
Information sourced from Uniprot.org
