Human KLF4 protein (Recombinant) (N-His) (STJP003272)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KLF4-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8Β°C for frequent use. Store at-20 to-80Β°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KLF4 |
| Gene ID | 9314 |
| Uniprot ID | KLF4_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu352-Phe513 |
Additional Info
| Function | Transcription factor.can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. |
| Protein Name | Krueppel-Like Factor 4Epithelial Zinc Finger Protein EzfGut-Enriched Krueppel-Like Factor |
| Database Links | Reactome: R-HSA-381340Reactome: R-HSA-422085Reactome: R-HSA-452723Reactome: R-HSA-9617828 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Protein Names | Krueppel-Like Factor 4 proteinEpithelial Zinc Finger Protein Ezf proteinGut-Enriched Krueppel-Like Factor proteinKLF4 proteinEZF proteinGKLF protein |
Information sourced from Uniprot.org