Human JSRP1 protein (Recombinant) (His-Tag) (STJP018442)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human JSRP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JSRP1 |
| Gene ID | 126306 |
| Uniprot ID | JSPR1_HUMAN |
| Accession Number | NP_653217.1 |
| Immunogen | Human |
| Immunogen Region | 1-331aa |
| Immunogen Sequence |
Additional Info
| Function | Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity. |
| Protein Name | Junctional Sarcoplasmic Reticulum Protein 1Junctional-Face Membrane Protein Of 45 Kda HomologJp-45 |
| Database Links | |
| Cellular Localisation | Sarcoplasmic Reticulum MembraneEndoplasmic Reticulum MembraneColocalizes With Ryanodine Receptors At The Sarcoplasmic Reticulum Triad Membranes |
| Alternative Protein Names | Junctional Sarcoplasmic Reticulum Protein 1 proteinJunctional-Face Membrane Protein Of 45 Kda Homolog proteinJp-45 proteinJSRP1 proteinJP45 protein |
Information sourced from Uniprot.org