Human Jagged1/JAG1/CD339 protein (Recombinant) (C-hFc) (STJP002673)

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STJP002673
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: JAG1
Gene ID: 182
Uniprot ID: JAG1_HUMAN
Immunogen Region: Trp896-Arg1065
Immunogen: Recombinant Human Jagged1/JAG1/CD339 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Trp896-Arg1065) of human Jagged-1/JAG1 (Accession #P78504) fused with an Fc tag at the C-terminus.
Immunogen Sequence: WCGPRPCLLHKGHSECPSGQ SCIPILDDQCFVHPCTGVGE CRSSSLQPVKTKCTSDSYYQ DNCANITFTFNKEMMSPGLT TEHICSELRNLNILKNVSAE YSIYIACEPSPSANNEIHVA ISAEDIRDDGNPIKEITDKI IDLVSKRDGNSSLIAAVAEV RVQRRPLKNR
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Protein Name Protein Jagged-1
Jagged1
Hj1
Cd Antigen Cd339
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2660826
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-8941856
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Reactome: R-HSA-9013507
Reactome: R-HSA-9013700
Reactome: R-HSA-9831926
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Protein Names Protein Jagged-1 protein
Jagged1 protein
Hj1 protein
Cd Antigen Cd339 protein
JAG1 protein
JAGL1 protein

Information sourced from Uniprot.org

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