Human ITLN1/Omentin protein (Recombinant) (N-His) (STJP005762)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ITLN1/Omentin-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ITLN1 |
| Gene ID | 55600 |
| Uniprot ID | ITLN1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Cys31-Gly253 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind human glycans. Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption. |
| Protein Name | Intelectin-1Itln-1Endothelial Lectin Hl-1Galactofuranose-Binding LectinIntestinal Lactoferrin ReceptorOmentin |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecretedEnriched In Lipid Rafts |
| Alternative Protein Names | Intelectin-1 proteinItln-1 proteinEndothelial Lectin Hl-1 proteinGalactofuranose-Binding Lectin proteinIntestinal Lactoferrin Receptor proteinOmentin proteinITLN1 proteinINTL proteinITLN proteinLFR proteinUNQ640 proteinPRO1270 protein |
Information sourced from Uniprot.org