Human IK protein (Recombinant) (N-GST) (STJP005286)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human IK-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | IK |
| Gene ID | 3550 |
| Uniprot ID | RED_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro192 |
Additional Info
| Function | Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1. (Microbial infection) Required, together with SMU1, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles. |
| Protein Name | Protein RedCytokine IkIk FactorProtein Rer |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleoplasmChromosomeCytoplasmCytoskeletonSpindle PolePredominantly Present Throughout The Nucleoplasm During PrometaphaseMetaphase And AnaphaseIs Also Detected In Nuclear Foci That Are Not Identical With Cajal BodiesStarts To Accumulate At Chromosomes During TelophaseAnd Is Nearly Exclusively Associated With Chromosomes In Newly Divided CellsColocalizes With Mad1l1 At Mitotic Spindle Poles During Metaphase And Anaphase |
| Alternative Protein Names | Protein Red proteinCytokine Ik proteinIk Factor proteinProtein Rer proteinIK proteinRED proteinRER protein |
Information sourced from Uniprot.org