Human IFT88 protein (Recombinant) (N-His) (STJP007331)

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STJP007331
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human IFT88-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: IFT88
Gene ID: 8100
Uniprot ID: IFT88_HUMAN
Immunogen Region: Arg481-Gly733
Immunogen: Homo sapiens (Human)
Function Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
Protein Name Intraflagellar Transport Protein 88 Homolog
Recessive Polycystic Kidney Disease Protein Tg737 Homolog
Tetratricopeptide Repeat Protein 10
Tpr Repeat Protein 10
Database Links Reactome: R-HSA-5610787
Reactome: R-HSA-5620924
Reactome: R-HSA-9613829
Reactome: R-HSA-9615710
Reactome: R-HSA-9646399
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Cell Projection
Cilium
Cilium Basal Body
Flagellum
Colocalizes With Entr1 And Gamma-Tubulin At The Basal Body Of Primary Cilia
Colocalizes With Entr1 And Pericentrin At The Centrosome
In Sperm Cells
Localizes To The Manchette
Head-Tail Coupling Apparatus And Flagellum
Alternative Protein Names Intraflagellar Transport Protein 88 Homolog protein
Recessive Polycystic Kidney Disease Protein Tg737 Homolog protein
Tetratricopeptide Repeat Protein 10 protein
Tpr Repeat Protein 10 protein
IFT88 protein
TG737 protein
TTC10 protein

Information sourced from Uniprot.org