| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human IFT88-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | IFT88 |
| Gene ID: | 8100 |
| Uniprot ID: | IFT88_HUMAN |
| Immunogen Region: | Arg481-Gly733 |
| Immunogen: | Homo sapiens (Human) |
| Function | Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment. |
| Protein Name | Intraflagellar Transport Protein 88 HomologRecessive Polycystic Kidney Disease Protein Tg737 HomologTetratricopeptide Repeat Protein 10Tpr Repeat Protein 10 |
| Database Links | Reactome: R-HSA-5610787Reactome: R-HSA-5620924Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9646399 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCell ProjectionCiliumCilium Basal BodyFlagellumColocalizes With Entr1 And Gamma-Tubulin At The Basal Body Of Primary CiliaColocalizes With Entr1 And Pericentrin At The CentrosomeIn Sperm CellsLocalizes To The ManchetteHead-Tail Coupling Apparatus And Flagellum |
| Alternative Protein Names | Intraflagellar Transport Protein 88 Homolog proteinRecessive Polycystic Kidney Disease Protein Tg737 Homolog proteinTetratricopeptide Repeat Protein 10 proteinTpr Repeat Protein 10 proteinIFT88 proteinTG737 proteinTTC10 protein |
Information sourced from Uniprot.org