Human HSPB8 protein (Recombinant) (His-Tag) (STJP016634)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HSPB8-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSPB8 |
| Gene ID | 26353 |
| Uniprot ID | HSPB8_HUMAN |
| Accession Number | NP_055180.1 |
| Immunogen | Human |
| Immunogen Region | 1-196aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Predominantly expressed in skeletal muscle and heart. |
| Function | Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity. |
| Protein Name | Heat Shock Protein Beta-8Hspb8Alpha-Crystallin C ChainE2-Induced Gene 1 ProteinHeat Shock Protein Family B Member 8Protein Kinase H11Small Stress Protein-Like Protein Hsp22 |
| Database Links | Reactome: R-HSA-3371571 |
| Cellular Localisation | CytoplasmNucleusTranslocates To Nuclear Foci During Heat Shock |
| Alternative Protein Names | Heat Shock Protein Beta-8 proteinHspb8 proteinAlpha-Crystallin C Chain proteinE2-Induced Gene 1 Protein proteinHeat Shock Protein Family B Member 8 proteinProtein Kinase H11 proteinSmall Stress Protein-Like Protein Hsp22 proteinHSPB8 proteinCRYAC proteinE2IG1 proteinHSP22 proteinPP1629 protein |
Information sourced from Uniprot.org