SDS-PAGE gel of recombinant human HSPB8 protein under reducing conditions Coomassie blue stain

Human HSPB8 protein (Recombinant) (His-Tag) (STJP016634)

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STJP016634
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Short Description :Recombinant-Human HSPB8-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:HSPB8
Gene ID:26353
Uniprot ID:HSPB8_HUMAN
Accession Number:NP_055180.1
Immunogen:Human
Immunogen Region:1-196aa
Immunogen Sequence: MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT
Tissue Specificity Predominantly expressed in skeletal muscle and heart.
Function Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity.
Protein Name Heat Shock Protein Beta-8
Hspb8
Alpha-Crystallin C Chain
E2-Induced Gene 1 Protein
Heat Shock Protein Family B Member 8
Protein Kinase H11
Small Stress Protein-Like Protein Hsp22
Database Links Reactome: R-HSA-3371571
Cellular Localisation Cytoplasm
Nucleus
Translocates To Nuclear Foci During Heat Shock
Alternative Protein Names Heat Shock Protein Beta-8 protein
Hspb8 protein
Alpha-Crystallin C Chain protein
E2-Induced Gene 1 Protein protein
Heat Shock Protein Family B Member 8 protein
Protein Kinase H11 protein
Small Stress Protein-Like Protein Hsp22 protein
HSPB8 protein
CRYAC protein
E2IG1 protein
HSP22 protein
PP1629 protein

Information sourced from Uniprot.org

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