| Short Description : | Recombinant-Human HIP/ST13-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M NaCl, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | ST13 |
| Gene ID: | 6767 |
| Uniprot ID: | F10A1_HUMAN |
| Accession Number: | NP_003923 |
| Immunogen: | Human |
| Immunogen Region: | 1-369aa |
| Immunogen Sequence: | MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRA |
| Function | One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins. |
| Protein Name | Hsc70-Interacting ProteinHipAging-Associated Protein 2Progesterone Receptor-Associated P48 ProteinProtein Fam10a1Putative Tumor Suppressor St13Renal Carcinoma Antigen Ny-Ren-33Suppression Of Tumorigenicity 13 Protein |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Hsc70-Interacting Protein proteinHip proteinAging-Associated Protein 2 proteinProgesterone Receptor-Associated P48 Protein proteinProtein Fam10a1 proteinPutative Tumor Suppressor St13 proteinRenal Carcinoma Antigen Ny-Ren-33 proteinSuppression Of Tumorigenicity 13 Protein proteinST13 proteinAAG2 proteinFAM10A1 proteinHIP proteinSNC6 protein |
Information sourced from Uniprot.org
