Human HIP/ST13 protein (Recombinant) (No-Tag) (STJP019651)

Name: Human HIP/ST13 protein (Recombinant) (No-Tag) (STJP019651)
SKU: STJP019651
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP019651

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Short Description	Recombinant-Human HIP/ST13-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M NaCl, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)

Gene Symbol	ST13
Gene ID	6767
Uniprot ID	F10A1_HUMAN
Accession Number	NP_003923
Immunogen	Human
Immunogen Region	1-369aa
Immunogen Sequence	MDPRKVNELR AFVKMCKQDP SVLHTEEMRF LREWVESMGG KVPPATQKAK SEENTKEEKP DSKKVEEDLK ADEPSSEESD LEIDKEGVIE PDTDAPQEMG DENAEITEEM MDQANDKKVA AIEALNDGEL QKAIDLFTDA IKLNPRLAIL YAKRASVFVK LQKPNAAIRD CDRAIEINPD SAQPYKWRGK AHRLLGHWEE AAHDLALACK LDYDEDASAM LKEVQPRA

Function	One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
Protein Name	Hsc70-Interacting Protein Hip Aging-Associated Protein 2 Progesterone Receptor-Associated P48 Protein Protein Fam10a1 Putative Tumor Suppressor St13 Renal Carcinoma Antigen Ny-Ren-33 Suppression Of Tumorigenicity 13 Protein
Database Links	Reactome: R-HSA-3371453
Cellular Localisation	Cytoplasm
Alternative Protein Names	Hsc70-Interacting Protein protein Hip protein Aging-Associated Protein 2 protein Progesterone Receptor-Associated P48 Protein protein Protein Fam10a1 protein Putative Tumor Suppressor St13 protein Renal Carcinoma Antigen Ny-Ren-33 protein Suppression Of Tumorigenicity 13 Protein protein ST13 protein AAG2 protein FAM10A1 protein HIP protein SNC6 protein

Information sourced from Uniprot.org