Human HFE protein (Recombinant) (His-Tag) (STJP017976)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HFE-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HFE |
| Gene ID | 3077 |
| Uniprot ID | HFE_HUMAN |
| Accession Number | NP_000401.1 |
| Immunogen | Human |
| Immunogen Region | 23-306aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in all tissues tested except brain. |
| Function | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
| Protein Name | Hereditary Hemochromatosis ProteinHla-H |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Hereditary Hemochromatosis Protein proteinHla-H proteinHFE proteinHLAH protein |
Information sourced from Uniprot.org