Human HDGF protein (Recombinant) (N-His) (STJP004888)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HDGF-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HDGF |
| Gene ID | 3068 |
| Uniprot ID | HDGF_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Tyr10-Leu240 |
Additional Info
| Post Translational Modifications | Sumoylated with SUMO1. Sumoylation prevents binding to chromatin. Phosphorylation at Ser-165 is likely to be required for secretion. |
| Function | Isoform 1: Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. Isoform 2: Does not have mitogenic activity for fibroblasts. Does not bind heparin. Isoform 3: Has mitogenic activity for fibroblasts. Heparin-binding protein. |
| Protein Name | Hepatoma-Derived Growth FactorHdgfHigh Mobility Group Protein 1-Like 2Hmg-1l2 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Isoform 1: NucleusCytoplasmSecretedExtracellular ExosomeSecreted By Exosomes And Is Located Inside The ExosomeMay Also Be Secreted As Free Protein Via An As Yet Unknown PathwayIsoform 2: NucleusSecreted By Exosomes And Is Located On The Outer Exosome SurfaceIsoform 3: Nucleus |
| Alternative Protein Names | Hepatoma-Derived Growth Factor proteinHdgf proteinHigh Mobility Group Protein 1-Like 2 proteinHmg-1l2 proteinHDGF proteinHMG1L2 protein |
Information sourced from Uniprot.org