Human HDGF protein (Recombinant) (N-His) (STJP004888)

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STJP004888
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HDGF-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: HDGF
Gene ID: 3068
Uniprot ID: HDGF_HUMAN
Immunogen Region: Tyr10-Leu240
Immunogen: Homo sapiens (Human)
Post Translational Modifications Sumoylated with SUMO1. Sumoylation prevents binding to chromatin. Phosphorylation at Ser-165 is likely to be required for secretion.
Function Isoform 1: Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. Isoform 2: Does not have mitogenic activity for fibroblasts. Does not bind heparin. Isoform 3: Has mitogenic activity for fibroblasts. Heparin-binding protein.
Protein Name Hepatoma-Derived Growth Factor
Hdgf
High Mobility Group Protein 1-Like 2
Hmg-1l2
Database Links Reactome: R-HSA-381038
Cellular Localisation Isoform 1: Nucleus
Cytoplasm
Secreted
Extracellular Exosome
Secreted By Exosomes And Is Located Inside The Exosome
May Also Be Secreted As Free Protein Via An As Yet Unknown Pathway
Isoform 2: Nucleus
Secreted By Exosomes And Is Located On The Outer Exosome Surface
Isoform 3: Nucleus
Alternative Protein Names Hepatoma-Derived Growth Factor protein
Hdgf protein
High Mobility Group Protein 1-Like 2 protein
Hmg-1l2 protein
HDGF protein
HMG1L2 protein

Information sourced from Uniprot.org

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