Human HAUS1 protein (Recombinant) (His-Tag) (STJP017608)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HAUS1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 0.2M NaCl, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HAUS1 |
| Gene ID | 115106 |
| Uniprot ID | HAUS1_HUMAN |
| Accession Number | NP_612452 |
| Immunogen | Human |
| Immunogen Region | 1-278aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver and heart. Weakly expressed in lung, brain and placenta. |
| Function | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. |
| Protein Name | Haus Augmin-Like Complex Subunit 1Coiled-Coil Domain-Containing Protein 5Enhancer Of Invasion-ClusterHei-C |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleSpindle PoleLocalizes With The Spindle Poles In Mitotic CellsIn MetaphaseLocalizes To The Mitotic Asters And Is Highly Punctate On The Microtubule ArrayDuring Later Stages Of MitosisRemains On The Spindle But Is Not Present At The InterzoneAnd Is Finally Observed At The Microtubule Bundles Proximal To The MidbodyClearly Excluded From The MidbodyIn ContrastDoes Not Colocalize With The Tubulin Cytoskeleton In Interphase CellsIn InterphaseLocalized At The Centrosome And Diffusely In The CytoplasmLocalizes To Mitotic Spindle Microtubules |
| Alternative Protein Names | Haus Augmin-Like Complex Subunit 1 proteinCoiled-Coil Domain-Containing Protein 5 proteinEnhancer Of Invasion-Cluster proteinHei-C proteinHAUS1 proteinCCDC5 proteinHEIC protein |
Information sourced from Uniprot.org